PT-2026-26154 · Samtools · Samtools

Published 2026-03-18 · Updated 2026-03-18 · CVE-2026-31973

NVD

CVSS v4.0

6.9

Medium

AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:L/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

SAMtools is a program for reading, manipulating and writing bioinformatics file formats. Starting in version 1.17, in the cram-size command, used to write information about how well CRAM files are compressed, a check to see if the cram decode compression header() was missing. If the function returned an error, this could lead to a NULL pointer dereference. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Fix

NULL Pointer Dereference

Weakness Enumeration

CWE-476

Related Identifiers

CVE-2026-31973

Affected Products

Samtools

References · 3

• https://nvd.nist.gov/vuln/detail/CVE-2026-31973 · Security Note
• https://github.com/samtools/samtools/security/advisories/GHSA-x86f-q6fj-cm43 · Note
• https://github.com/samtools/samtools/commit/06fc2a219b3d7c94d3f412c09f6d1efd51199f2f · Note